Microvascular Therapeutics & Imaging Laboratory
Department of Biomedical Engineering & Beckman Laser Institute
University of California, Irvine
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Publications

2009

Y.C. Huang, N. Tran, P.R. Shumaker, K. Kelly, E.V. Ross, J.S. Nelson, B. Choi, "Blood Flow Dynamics after Laser Therapy of Port Wine Stain Birthmarks," Laser. Surg. Med., Vol. 41, No. 8, pp 563-571 (2009). [pdf]

M. Zimmerley, R.A. McClure, B. Choi, E.O. Potma, "Following dimethyl sulfoxide skin optical clearing dynamics with quantitative nonlinear multimodal microscopy," Appl. Optics., Vol. 48, No. 10, pp. D79-D87 (2009). [pdf]

A.K. Bui, R.A. McClure, J. Chang, C. Stoianovici, J. Hirshburg, A.T. Yeh, B. Choi, "Revisiting optical clearing with dimethyl sulfoxide (DMSO)," Laser. Surg. Med., Vol. 41, No. 2, pp. 142-148 (2009). [pdf]

2008

J. Channual, B. Choi, D. Pattanachinda, J. Lotfi, K.M. Kelly, "Long-term vascular effects of photodynamic and pulse dye laser therapy protocols," Laser. Surg. Med. (2008, in press).

J.H. Yoon, T.Y. Son, E.H. Choi, B. Choi, J.S. Nelson, B.J. Jung, "Enhancement of skin clearing efficacy using a micro-needle roller," J. Biomed. Opt. (2008). [pdf]

W. Verkruysse, B. Choi, J.R. Zhang, J.H. Kim, J.S. Nelson, "Thermal depth profiling of vascular lesions: Automated regularization of reconstruction algorithms," Phys. Med. Biol. (2008). [pdf]

Y.C. Huang, T.L. Ringold, J.S. Nelson, B. Choi, "Noninvasive blood flow imaging for real-time feedback during laser therapy of port wine stain birthmarks," Laser. Surg. Med., Vol. 40, No. 3, pp. 167-173 (2008). [pdf]

J.C. Ramirez-San-Juan, R. Ramos-Garcia, I. Guizar-Iturbide, G. Martinez-Niconoff, B. Choi, "Simplified algorithm for laser speckle imaging of blood flow dynamics," Opt. Express, Vol. 16, No. 5, pp. 3197-3203 (2008). [pdf]

B. Choi, W.C. Jia, J. Channual, K.M. Kelly, J. Lotfi, "The importance of long-term monitoring of the microvascular response to light-based therapies," J. Invest. Dermatol., Vol. 128, No. 2, pp. 485-488 (2008). [pdf]

2007

W.C. Jia, B. Choi, W. Franco, J. Lotfi, B. Majaron, G. Aguilar, J.S. Nelson, "Treatment of cutaneous vascular lesions using multiple-intermittent cryogen spurts and two-wavelength laser pulses: Numerical and animal studies," Laser. Surg. Med., Vol. 39, No. 6, pp. 494-503 (2007). [pdf]

J. Hirshburg, B. Choi, J.S. Nelson, A.T. Yeh, "Correlation between collagen solubility and skin optical clearing using sugars," Laser. Surg. Med., Vol. 39, No. 2, pp. 140-144 (2007). [pdf]

2006

B.J. Jung, C.S. Kim, B. Choi, J.S. Nelson, "Hand-held pulsed photothermal radiometry system to estimate epidermal temperature rise during laser therapy," Skin Res. Technol., Vol. 12, No. 4, pp. 292-297 (2006). [pdf]

B. Choi, J.C.  Ramirez-San-Juan, J. Lotfi, J.S. Nelson, "Linear response range characterization and in vivo application of laser speckle imaging of blood flow dynamics," J. Biomed. Opt., Vol. 11, No. 4, article 041129 (2006). [pdf]

J. Hirshburg, B. Choi, J.S. Nelson, A.T. Yeh, "Collagen solubility correlates with skin optical clearing," J. Biomed. Opt., Vol. 11, No. 4, article 040501 (2006). [pdf]

T.K. Smith, B. Choi, J.C. Ramirez-San-Juan, J.S. Nelson, K. Osann, K.M. Kelly, "Microvascular blood flow dynamics associated with photodynamic therapy, pulsed dye laser irradiation and combined regimens," Laser. Surg. Med., Vol. 38, No. 5, pp. 532-539 (2006). [pdf]

R. Zhang, J.C. Ramirez-San-Juan, B. Choi, W.C. Jia, G. Aguilar, K.M. Kelly, J.S. Nelson, "Thermal responses of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses," Laser. Surg. Med., Vol. 38, No. 2, pp. 137-141 (2006). [pdf]

J.C. Ramirez-San-Juan, B. Choi, W. Franco, J.S. Nelson, G. Aguilar, "Effect of ambient humidity on light transmittance through skin phantoms during cryogen spray cooling," Phys. Med. Biol., Vol. 51, pp. 113-120 (2006). [pdf]

2005

B. Jung, C.S. Kim, B. Choi, K.M. Kelly, J.S. Nelson, "Use of erythema index imaging for systematic analysis of port wine stain skin response to laser therapy," Laser. Surg. Med., Vol. 37, pp. 186-191 (2005). [pdf]

K.M. Kelly, B. Choi, S. McFarlane, A. Motosue, B. Jung, M.H. Khan, J.C. Ramirez-San-Juan, J.S. Nelson, "Description and analysis of treatments for port wine stain birthmarks," Arch. Fac. Plast. Surg., Vol. 7, No. 5, pp. 287-294 (2005). [pdf]

C.S. Kim, M.K. Kim, B. Jung, B. Choi, W. Verkruysse, M.Y. Jeong, J.S. Nelson, "Determination of an optimized conversion matrix for device independent skin color image analysis: Monitoring port wine stain response to laser therapy," Laser. Surg. Med., Vol. 37, pp. 138-143 (2005). [pdf]

B. Majaron, M. Milanic, B. Choi, J.S. Nelson, "Selecting optimal radiation detector for temperature profiling in human skin using pulsed photothermal radiometry," Journal de Physique IV - Proceedings, Vol. 125, pp. 737-739 (2005). [pdf]

B. Jung, B. Choi, Y. Shin, A.J. Durkin, J.S. Nelson, "Determination of optimal view angles for quantitative facial image analysis," J. Biomed. Opt., Vol. 10, No. 2, article 024002 (2005). [pdf]

R. Zhang, W. Verkruysse, B. Choi, J.A. Viator, B. Jung, L. Svaasand, G. Aguilar, J.S. Nelson, "Determination of human skin optical properties from spectrophotometric measurements based on optimization by genetic algorithms," J. Biomed. Opt., Vol. 10, No. 2, article 024030 (2005). [pdf]

S. Kimel, B. Choi, L.O. Svaasand, J. Lotfi, J.A. Viator, J.S. Nelson, "Influence of laser wavelength and pulse duration on gas bubble formation in blood filled glass capillaries," Laser. Surg. Med., Vol. 36, No. 4, pp. 281-288 (2005). [pdf]

B. Choi, L.V. Tsu, E. Chen, T.S. Ishak, S.M. Iskandar, S. Chess, J.S. Nelson, "Determination of chemical agent optical clearing potential using in vitro human skin," Laser. Surg. Med., Vol. 36, No. 2, pp.72-75 (2005). [pdf]

W. Verkruysse, B. Majaron, B. Choi, J.S. Nelson, "Combining singular value decomposition and a non-negative constraint in a hybrid method for photo-thermal depth profiling," Rev. Sci. Instrum., Vol. 76, No.2, article 024301, pp. 1-6 (2005). [pdf]

C.S. Kim, B. Choi, J.S. Nelson, Q. Li, P. Zare Dashti, H.P. Lee, "Compensation of polarization-dependent loss in transmission fiber gratings using a Sagnac loop interferometer," Opt. Lett., Vol. 30, No. 1., pp. 20-22 (2005). [pdf]

W. Verkruysse, R. Zhang, B. Choi, G. Aguilar, G. Lucassen, L.O. Svaasand, J.S. Nelson, "A library based fitting method for visual reflectance spectroscopy of human skin," Phys. Med. Biol., Vol. 50, No. 1, pp. 57-70 (2005). [pdf]

2004

C.S. Kim, Y.G. Han, J.U. Kang, B. Choi, J.S. Nelson, "Polarization-insensitive multi-wavelength switching based on polarization-sensitive long-period fiber gratings," Opt. Express, Vol. 12, No. 24, pp. 6082-6087 (2004). [pdf]

H. Lee, R.T. Ryan, J. Kim, B. Choi, N.V. Arakeri, J.M.H. Teichman, A.J. Welch, "Dependence of calculus retropulsion dynamics on fiber size and radiant exposure during Ho:YAG lithotripsy," J. Biomech. Eng., Vol. 126, No. 4, pp. 506-515 (2004). [pdf]

M.H. Khan, S. Chess, B. Choi, K.M. Kelly, J.S. Nelson, "Can topically applied optical clearing agents increase the epidermal damage threshold and enhance therapeutic efficacy?," Laser. Surg. Med., Vol. 35, No. 2, pp. 93-95 (2004). [pdf]

B. Choi, N.M. Kang, J.S. Nelson, "Laser speckle imaging for monitoring blood flow dynamics in the in vivo rodent dorsal skin fold model," Microvasc. Res., Vol. 68, No. 2, pp. 143-146 (2004). [pdf]

J.A. Viator, J. Komadina, L.O. Svaasand, G. Aguilar, B. Choi, J.S. Nelson, "A comparative study of photoacoustic and reflectance methods for determination of epidermal melanin content," J. Invest. Dermatol., Vol. 122, No. 6, pp. 1432-1439 (2004).

B. Choi, T.E. Milner, J. Kim, J.D. Goodman, G. Vargas, G. Aguilar, and J.S. Nelson, "Use of optical coherence tomography to monitor biological tissue freezing during cryosurgery," J. Biomed. Optics, Vol. 9, No. 2, pp. 282-286 (2004).

B. Choi, B. Majaron, J.S. Nelson, "Computational model to evaluate port wine stain depth profiling using pulsed photothermal radiometry," J. Biomed. Optics, Vol. 9, No. 2, pp. 299-307 (2004). [pdf]

M. Khan, B. Choi, S. Chess, K. Kelly, J. McCullough, J.S. Nelson, "Optical clearing of in vivo human skin: Implications for light-based diagnostic imaging and therapeutics," Laser. Surg. Med., Vol. 34, No. 2, pp. 83-85 (2004). [pdf]

B. Jung, B. Choi, A.J. Durkin, K.M. Kelly, J.S. Nelson, "Characterization of port wine stain skin erythema and melanin content using cross-polarized diffuse reflectance imaging," Laser. Surg. Med., Vol. 34, No. 2, pp. 174-181 (2004). [pdf]

2003

B. Choi, E.D. Jansen, A.J. Welch, "Acoustic-based measurements of material absorption coefficients: Relationship between laser pulse duration and stress confinement time," J. Appl. Phys., Vol. 94, No. 12, pp. 7826-7831 (2003).

A. Yeh, B. Choi, J.S. Nelson, B.J. Tromberg, "Reversible dissociation of collagen in tissues," J. Invest. Dermatol, Vol. 121, No. 12, pp. 1332-1335 (2003). [pdf]

J.A. Viator, B. Choi, J.S. Nelson, M. Ambrose, J. Spanier, "In vivo port-wine stain depth determination with a photoacoustic probe," Appl. Optics, Vol. 42, No. 16, pp. 3215-3224 (2003).

A. Edris, B. Choi, G. Aguilar, J.S. Nelson, "Measurements of laser light attenuation following cryogen spray cooling spurt termination," Laser. Surg. Med., Vol. 32, No. 2, pp. 143-147 (2003).

J.A. Viator, B. Choi, G.M. Peavy, S. Kimel, J.S. Nelson, "Spectra from 2.5-15  m of tissue phantom materials, optical clearing agents, and ex vivo human skin: Implications for depth profiling of human skin," Phys. Med. Biol., Vol 48, No. 2, pp. N15-N24 (2003). [pdf]

H. Lee, R.T. Ryan, J.M.H. Teichman, J. Kim, B. Choi, N.V. Arakeri, A.J. Welch, "Stone retropulsion during holmium:YAG lithotripsy," J. Urology, Vol. 169. No. 3, pp. 881-885 (2003).

2002

B. Choi, J. Kim, A.J. Welch, J.A. Pearce, "Dynamic impedance measurements during radio frequency heating of the cornea," IEEE Trans. Biomed. Eng., Vol. 49, No. 12, pp. 1610-1616 (2002).

B. Choi and A.J. Welch, "Infrared imaging of 2-D temperature distribution during cryogen spray cooling," J. Biomech. Eng., Vol. 124, No. 6, pp. 669-675 (2002).

D.X. Hammer, D. Davé, T.E. Milner, B. Choi, H.G. Rylander III, A.J. Welch, "Investigation of the transduction mechanism of infrared detection in Melanophila acuminata: Photo-thermal-mechanical hypothesis," Comp. Biochem. Phys. A, Vol. 132, No. 2, pp. 381-392 (2002).

2001

K.F. Chan, B. Choi, G. Vargas, D.X. Hammer, B. Sorg, T.J. Pfefer, J.M.H. Teichman, A.J. Welch, E.D. Jansen, "Free electron laser ablation of urinary calculi: An experimental study," IEEE J. Sel. Top. Quant. Elect., Vol. 7, No. 6, pp. 1022-1033 (2001).

B. Choi and A.J. Welch, "Analysis of thermal relaxation following laser irradiation of tissue," Laser. Surg. Med., Vol. 29, No. 4, pp. 351-359 (2001). [pdf]

2000

T.J. Pfefer, B. Choi, G. Vargas, K.M. McNally, A.J. Welch, "Pulsed laser-induced thermal damage in whole blood," J. Biomech. Eng., Vol. 122, No. 2, pp. 196-202 (2000).

K.F. Chan, D.X. Hammer, B. Choi, J.M.H. Teichman, H.S. McGruff, H. Pratisto, E.D. Jansen, A.J. Welch, "Free electron laser lithotripsy: Threshold radiant exposures," J. Endourol., Vol. 14, No. 2, pp. 161-167 (2000).

B. Choi, J.A. Pearce, A.J. Welch, "Modeling infrared temperature measurements: Implications for laser irradiation and cryogen cooling studies," Phys. Med Biol., Vol. 45, No. 2, pp. 541-557 (2000).

1999

N.M. Fried, B. Choi, A.J. Welch, J.T. Walsh, Jr., "Radiometric surface temperature measurements during dye-assisted laser skin closure: In vitro and in vivo results," Laser. Surg. Med., Vol. 25, pp. 291-303 (1999).

B. Choi, J.K. Barton, E.K. Chan, S.L. Thomsen, A.J. Welch, "Thermographic and histologic evaluation of laser skin resurfacing scans," IEEE J. Sel. Top. Quant. Elect., Vol. 5, No. 4, pp. 1116-1126 (1999).

1998

B. Choi, J.K. Barton, E.K. Chan, A.J. Welch, "Imaging of the irradiation of skin with a clinical CO2 laser system: Implications for laser skin resurfacing," Laser. Surg. Med., Vol. 23, No. 4, pp. 185-193 (1998).

Last Modified: Friday, October 16, 2009